A systematic review of scope of studies related to antimicrobial resistance and antibiotic use among children in Vietnam

 https://doi.org/10.52322/jocmbmh.07.en.03

ABSTRACT

Objectives: This review aims to assess scope of available studies related to antimicrobial resistance and antibiotic use among children in Vietnam.

Material and Methods: Systematic review of original research and narrative review of legal documents/policies up to December 2019. International publications were searched using PubMed and Web of Science. Policy documents were accessed through the national database of legal documents.

Results: We included 32 originial studies and 19 legal documents in the final review. Most of studies related to AMR and AMU among children in Vietnam were funded and supported by international entities, while there is a lack of support from the national funds. The majority of studies was focused on microbiology and molecular biology topic. Assessments of interventions that raise awareness and antibiotics management in hospitals and communities are still very limited. No study on health economics or policy impact have been performed. The study design were mostly descriptive cross-sectional with very few cohort studies and clinical randomized trials. In the context of limited understanding and evaluation of AMR amongst children, interventions remain few and far between. Regarding legal/policy documents, most of them were issued by the Ministry of Health and many of which are general guidelines, decisions, or circulars on antibiotic resistance monitoring, use of antibiotics and infection control. Few documents refer directly to the target of children. Documents at the local level are limited.

Conclusion: The results of this research provide important evidence giving directions for future research and policies regarding antibiotics usage among children in Viet Nam in the future.

Keywords: Antimicrobial resistance, antibiotic use, children, Vietnam, review

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