Evaluating the associations between embryo morphokinetics and results of pre-implantation genetic testing

https://doi.org/10.52322/jocmbmh.12.en.0108

ABSTRACT

Objective: To assess the utility of time-lapse (TL) imaging in selecting embryos for preimplantation genetic testing (PGT) biopsy.

Methods: We retrospectively analyzed embryos that were cultured with TL imaging and selected for PGT biopsy.

Results: The embryos selected for biopsy primarily had KIDScore grades ranging from 5-9 points. Embryos selected using TL imaging had higher rates of genetically normal results and lower rates of abnormalities compared to embryos selected using conventional morphology assessment. Early-cleaving embryos that divided from the zygote stage to 5 blastomeres faster had higher genetic normalcy rates than slower dividing embryos.

Conclusions: TL imaging improves embryo selection for PGT by enabling the identification of embryos with higher viability and genetic competency.

Keywords: Timelapse, preimplantation genetic testing, embryo selection

 

Citations:

APA: Nguyen Thi Thanh Thao, & Dao Lan Huong. (2023). Evaluating the associations between embryo morphokinetics and results of pre-implantation genetic testing. Journal of Clinical Medicine, 1(12), 47-52.

AMA: Thao NTT, Huong DL. Evaluating the associations between embryo morphokinetics and results of pre-implantation genetic testing. J Clin Med. 2023;1(12):47-52.

MLA: Thao, Nguyen Thi Thanh, and Dao Lan Huong. "Evaluating the Associations Between Embryo Morphokinetics and Results of Pre-implantation Genetic Testing." Journal of Clinical Medicine, vol. 1, no. 12, 2023, pp. 47-52.

Vancouver: Thao NTT, Huong DL. Evaluating the associations between embryo morphokinetics and results of pre-implantation genetic testing. J Clin Med. 2023;1(12):47-52.

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