Peripheral blood oxygen saturation (Spo2) value in the diagnosis of congenital heart disease in newborns at the Pediatric Center, Bach Mai Hospital

https://doi.org/10.52322/jocmbmh.12.en.0113

ABSTRACT

Introduction: Pulse oximetry has been suggested as a screening test for congenital heart disease (CHD) in asymptomatic newborns. However, routine pulse oximetry testing in newborns before discharge from the hospital has not been evaluated.

Objective: To evaluate pulse oximetry as a screening test for critical congenital heart disease (CCHD) in newborns admitted to the Pediatric Center at Bach Mai Hospital.

Methods: We conducted a cross-sectional study of newborns between November 2020 and November 2021. Pulse oximetry was measured upon admission to the Pediatric Center, and a Doppler echocardiogram was performed on all newborns. Cases with oxygen saturation <95% and a difference of >3% between the right hand and right leg were compared to other cases.

Results: Out of 707 newborns screened, 101 had cardiac abnormalities, including: patent ductus arteriosus (62.4%), atrial septal defect (13.9%), ventricular septal defect (11.8%), Ebstein anomaly (2.9%), mild-moderate coarctation of the aorta (2.0%), and mild-moderate pulmonary valve stenosis (1.0%). Upon admission, 43.8% of newborns with CHD had a right hand-right leg difference >3%. Admission pulse oximetry had a specificity of 74.1%, corresponding to a negative predictive value of 88.7%. Similarly, in the severe disease group, admission pulse oximetry had a sensitivity of 80% and a specificity of 71.8% with a negative predictive value of 99.8%.

Conclusions: Abnormal pulse oximetry has a high sensitivity for detecting severe CHD. The negative predictive value of pulse oximetry for severe CHD is very high. Abnormal pulse oximetry suggests a high probability of CHD, but normal pulse oximetry does not exclude CHD and needs to be combined with evaluation for abnormal clinical signs.

Keywords: SpO₂, Congenital heart disease, newborn

 

Citations:

APA: Nguyen Thanh Nam, Le Dieu Linh, Pham Thi Mai, Nguyen Huu Hieu, & Pham Van Dem. (2023). Peripheral blood oxygen saturation (Spo2) value in the diagnosis of congenital heart disease in newborns at the Pediatric Center, Bach Mai Hospital. Journal of Clinical Medicine, 1(12), 93-100.

AMA: Nam NT, Linh LD, Mai PT, Hieu NH, Dem PV. Peripheral blood oxygen saturation (Spo2) value in the diagnosis of congenital heart disease in newborns at the Pediatric Center, Bach Mai Hospital. J Clin Med. 2023;1(12):93-100.

MLA: Nam, Nguyen Thanh, et al. "Peripheral Blood Oxygen Saturation (Spo2) Value in the Diagnosis of Congenital Heart Disease in Newborns at the Pediatric Center, Bach Mai Hospital." Journal of Clinical Medicine, vol. 1, no. 12, 2023, pp. 93-100.

Vancouver: Nam NT, Linh LD, Mai PT, Hieu NH, Dem PV. Peripheral blood oxygen saturation (Spo2) value in the diagnosis of congenital heart disease in newborns at the Pediatric Center, Bach Mai Hospital. J Clin Med. 2023;1(12):93-100.

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