Evaluation of the left ventricular function of patients with severe heart failure before and after implantation of cardial resynchronization (CRT) devices using Speckle tracking echocardiography (STE)

https://doi.org/10.52322/jocmbmh.12.en.0109

ABSTRACT

Objective: This study aims to evaluate left ventricular function of patients with severe heart failure before and after the implantation of cardial resynchronization therapy (CRT) devices using Speckle tracking echocardiography.

Methods: We conducted a prospective longitudinal study with a convenient sample size of 22 patients with severe heart failure (left ventricular ejection fraction (LVEF) ≤ 35% and QRS duration ≥ 120 msec) who underwent CRT device implantation at Vietnam National Heart Institute - Bach Mai Hospital.

Results: The mean age of patients in our study was 60 years old, and men accounted for 84.8%. The mean baseline QRS duration was 133.9 msec. The QRS duration at the time of discharge was 124.4 msec, compared to 115.6 msec at 1 month and 111.8 msec at 3 months of follow-up. The severity of mitral regurgitation improved while there was a decrease in pulmonary artery systolic pressure after CRT implantation and during the follow-up (both p<0.05). The diastolic left ventricular function improved significantly at 1 month after CRT implantation, with a decrease in the E/e’ ratio and an increase in e’, a’, and s’ velocities (both p<0.05). The left ventricular global longitudinal strain (LVGLS) improved at 1 month after CRT implantation.

Conclusions: Patients undergoing CRT implantation had a narrowing of the QRS duration from 133.9 msec to 111.8 msec over a 3-month follow-up. The severity of mitral regurgitation and the pulmonary artery systolic pressure both decreased after CRT implantation. The statistically significant reduction in E/e’ was observed right after CRT implantation. Meanwhile, e’, a’, and s’ velocities started to experience a statistically significant increase at 1 month after CRT implantation. The left ventricular global longitudinal strain improved markedly after 1 month of CRT implantation.

Keywords: Speckle tracking echocardiography (STE), heart failure, cardial resynchronization

 

Citations:

APA: Hoang Thi Phu Bang, Vien Hoang Long, Do Doan Loi, & Truong Thanh Huong. (2023). Evaluation of the left ventricular function of patients with severe heart failure before and after implantation of cardial resynchronization (CRT) devices using Speckle tracking echocardiography (STE). Journal of Clinical Medicine, 1(12), 53-59.

AMA: Bang HTP, Long VH, Loi DD, Huong TT. Evaluation of the left ventricular function of patients with severe heart failure before and after implantation of cardial resynchronization (CRT) devices using Speckle tracking echocardiography (STE). J Clin Med. 2023;1(12):53-59.

MLA: Bang, Hoang Thi Phu, et al. "Evaluation of the Left Ventricular Function of Patients with Severe Heart Failure Before and After Implantation of Cardial Resynchronization (CRT) Devices Using Speckle Tracking Echocardiography (STE)." Journal of Clinical Medicine, vol. 1, no. 12, 2023, pp. 53-59.

Vancouver: Bang HTP, Long VH, Loi DD, Huong TT. Evaluation of the left ventricular function of patients with severe heart failure before and after implantation of cardial resynchronization (CRT) devices using Speckle tracking echocardiography (STE). J Clin Med. 2023;1(12):53-59.

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